Caldwell Memorial Hospital Becomes Regional Leader In Cervical Cancer Screening Technology

Lenoir's leader in women's healthcare offers advanced cervical cancer screening system

Lenoir, N.C. - October 11, 2006 - Caldwell Memorial Hospital today announced the implementation of the ThinPrep® Imaging System for cervical cancer screening. The ThinPrep Imaging System, approved by the U.S. Food and Drug Administration (FDA), is the first fully integrated, interactive computer system that assists cytotechnologists and pathologists in the primary screening of ThinPrep®Pap Test slides. The ThinPrep Imaging System combines revolutionary imaging technology with human interpretive expertise to improve cervical cancer screening efficiency and performance. Caldwell Memorial Hospital has been offering the ThinPrep Pap Test since 1996 and will use the ThinPrep Imaging System for all cervical cancer screenings.

"Caldwell Memorial Hospital is committed to providing our patients with the best new technology to detect disease early and the ThinPrep® System enables us to do that," said George Nichols, M.D. "Using the ThinPrep System offers significant improvements over previous screening technologies. Making this technology the standard in our practice was simply the right thing to do."

According to American Cancer Society estimates, nearly 10,000 women in the United States will be diagnosed with cervical cancer in 2006 and about 3,700 will die of the disease. Cervical cancer is almost 100 percent curable if detected early. More than 30 published studies with more than 500,000 patients have demonstrated the improved performance of the ThinPrep Pap Test compared to the conventional Pap smear. A meta-analysis published in the American Journal of Obstetrics and Gynecology concluded that the ThinPrep Pap Test improves diagnosis of low-grade (LSIL) and high-grade squamous intraepithelial lesions (HSIL) compared to the conventional Pap smear. This comprehensive study also demonstrated improved sample adequacy with the ThinPrep method.

The ThinPrep Pap Test is a liquid-based test that employs a fluid medium to collect and preserve cervical cells.  Specimens are first collected by the clinician with a cervical sampling device as is normally done so there is no difference for the patient; then, instead of smearing the cells on a slide, the device is rinsed into a ThinPrep vial containing PreservCyt® transport medium, capturing virtually all of the cells. The specimen is then sent to the laboratory where a ThinPrep Processor eliminates obscuring debris and distributes a uniform, representative thin-layer of cells on a microscope slide. The ThinPrep System improves the quality of the specimen, which can result in more accurate diagnoses and fewer unnecessary repeat tests.

Caldwell Memorial Hospital is the private, not-for-profit, community hospital in Lenoir, North Carolina.  The mission of Caldwell Memorial Hospital is to provide safe, effective, compassionate care and to promote healthy lifestyles to our community.

Divisions of Caldwell Memorial Hospital include: The Allene Broyhill Stevens Heilman Radiation Oncology Center; The Alvin W. Daughtridge Arthritis Clinic; The Ambulatory Infusion Center; Caldwell Acute Care Specialists; Caldwell FamilyCare Center; Caldwell Internal Medicine; The Caldwell Physician Network; Caldwell Urology Associates; The Center for Breast Health; The Center for Diabetes Health; The Center for Joint Care; The Falls Medical Park; Foothills Lymphedema Treatment Center; The George M. Hancock Surgery Center; Main Street Medical Park; Mulberry Pediatrics; The Pain Management Center; Quest4Life Rehabilitation Services; The Quest4Life Wellness Center; Southfork Medical Park; Westpointe Medical Practice and The William E. Stevens, Jr. Cancer Care Center.  Hallmark Family Physicians is a wholly-owned subsidiary of Caldwell Memorial Hospital.

About Cytyc Corporation: Cytyc Corporation, located in Marlborough, Massachusetts, designs, develops, manufactures, and markets the ThinPrep® System for use in medical diagnostic applications primarily focused on women's health. The ThinPrep System consists of the ThinPrep® 2000 Processor, ThinPrep® 3000 Processor, ThinPrep® Imaging System, and related reagents, filters, and other supplies.  Cytyc is traded on The Nasdaq Stock Market under the symbol CYTC. Cytyc and ThinPrep are registered trademarks of Cytyc Corporation.